How often do rare blood clots occur after AstraZeneca vaccination?

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Rare Blood Clots Occur in Approximately One in 100,000 Vaccinated Individuals

The European Medicines Agency (EMA) has determined that the benefits of the AstraZeneca Covid-19 vaccine, Vaxzevria, continue to outweigh its risks for adults across all age groups. This assessment comes despite the identification of very rare instances of blood clots occurring in conjunction with low platelet counts following vaccination. These specific rare clotting events have been observed in approximately one in every 100,000 individuals who received the vaccine.
Benefits Outweigh Risks Across Age Groups

The EMA's comprehensive review concluded that the advantages of receiving the Vaxzevria vaccine, particularly in preventing severe outcomes of Covid-19, are substantial. The agency highlighted that the vaccine is effective in averting hospitalisations, intensive care unit admissions, and deaths attributable to the virus. Furthermore, the benefits associated with vaccination are noted to increase proportionally with advancing age and higher infection rates within populations.
Identification of Rare Side Effects

While generally mild or moderate side effects are common and transient, the EMA has acknowledged the occurrence of a very rare but serious condition involving blood clots alongside low blood platelets. This specific adverse event has been the subject of significant scrutiny. The regulator has documented a worldwide total of 287 cases of these rare clots that have been linked to the AstraZeneca vaccine.
Global Case Counts of Rare Clots

Beyond the cases associated with AstraZeneca, the EMA's surveillance has identified other instances of rare clots linked to different Covid-19 vaccines. These include 25 cases associated with the Pfizer-BioNTech vaccine, eight with the Johnson & Johnson vaccine, and five with the Moderna jab. The EMA stated that there was insufficient data available across the European Union to provide further context regarding benefits and risks in relation to sex, despite some reports suggesting a higher prevalence among women.

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How often do rare blood clots occur after AstraZeneca vaccination?

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