How serious are the poisoning cases from Ivermectin use?

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Two individuals in Malaysia experienced acute poisoning following the self-administration of Ivermectin.

Two individuals in Malaysia have suffered acute poisoning after consuming Ivermectin, a drug not approved for Covid-19 treatment or prevention in the country. One case involved a 35-year-old who experienced five days of breathing difficulties after taking a single pill, while another involved a senior citizen found unconscious after ingesting 15 pills at once. Both incidents were reported to the National Poisons Centre, highlighting the significant risks associated with self-medication.
Severity of Reported Poisoning Incidents

The Health Ministry has detailed two severe instances of Ivermectin poisoning. A 35-year-old individual developed breathing difficulties that persisted for five days subsequent to consuming one Ivermectin pill. In a more critical situation, a senior citizen was discovered unconscious after reportedly taking 15 Ivermectin pills simultaneously. These cases underscore the potential for acute and dangerous reactions to the drug when self-administered.
Risks Associated with Unapproved Drug Use

The ministry cautioned against using Ivermectin for self-treatment against Covid-19, noting its illicit sale in the market. Ingesting this unapproved medication at incorrect dosages can lead to poisoning. While minor side effects may include nausea, giddiness, diarrhoea, and stomach discomfort, the potential for severe consequences such as low blood pressure, lung damage, and even death is a significant concern.
Lack of Antidote and Global Approval

A critical aspect of Ivermectin poisoning is the current absence of an antidote or specific treatment for affected individuals. Furthermore, no worldwide health body has sanctioned the use of Ivermectin for either the treatment or prevention of Covid-19. Even countries that previously permitted its use, such as India, have since reversed their decisions, indicating a lack of international consensus on its efficacy and safety for this purpose.

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How serious are the poisoning cases from Ivermectin use?

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