What are the most common side effects reported for Spikevax?

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The Most Common Side Effects Reported for Spikevax Include Localized Reactions and Systemic Symptoms

Clinical trial participants who received the Moderna Covid-19 vaccine, also known as Spikevax, most frequently reported localized reactions at the injection site, such as pain, alongside systemic symptoms. These commonly reported side effects encompass fatigue, headaches, muscle or joint pain, chills, and nausea or vomiting. Additionally, some individuals experienced swollen lymph nodes following vaccination.
Localized and Systemic Reactions Were Prevalent in Trials

During clinical trials involving 14,287 vaccine recipients and 14,164 placebo recipients, a range of adverse events were documented. The most frequently observed side effects were pain at the injection site, fatigue, and headaches. Other commonly reported issues included muscle or joint pain, chills, and gastrointestinal symptoms like nausea or vomiting.
Swollen Lymph Nodes Also Noted

Beyond the more commonly cited reactions, swollen lymph nodes were also identified as a reported side effect among participants in the clinical trials for Spikevax. This finding is consistent with observations in other vaccine studies where lymph node swelling can occur as a sign of the immune system's response.
Increased Risk of Myocarditis and Pericarditis in Young Men

The U.S. Food and Drug Administration (FDA) noted a specific increased risk associated with myocarditis, an inflammation of the heart muscle, and pericarditis, an inflammation of the tissue surrounding the heart. This elevated risk was observed in men aged 18 to 24, particularly following the administration of the second dose of the vaccine. Despite this finding, the FDA determined that the benefits of the Spikevax vaccine outweigh the risks of myocarditis and pericarditis for individuals aged 18 and older.

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What are the most common side effects reported for Spikevax?

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