What is the impact of carbohydrates on weight gain in mice?

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Carbohydrates Showed No Impact on Weight Gain in Mice

Research conducted on mice indicates that carbohydrates, even when comprising up to 30% of caloric intake from sugar, did not result in weight gain. Furthermore, combining sugar with fat did not amplify the weight gain effects beyond that of fat consumed alone.
Absence of Carbohydrate-Induced Weight Gain

The study, which involved feeding mice a variety of diets over three months, found no correlation between carbohydrate consumption and increased body weight. This held true even when the carbohydrate component included significant amounts of sugar.
Fat as the Sole Dietary Driver of Weight Gain

In contrast to carbohydrates, dietary fat was identified as the sole component linked to increased energy intake and subsequent weight gain in the experimental mice. This suggests that fat uniquely stimulates brain reward centres, leading to greater consumption.
Protein and Sugar's Limited Role

The research also found no evidence that low protein levels stimulated greater food intake, indicating the absence of a specific protein target driving overconsumption. Similarly, the inclusion of sugar within carbohydrate intake did not independently contribute to weight gain.

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What is the impact of carbohydrates on weight gain in mice?

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